Helix Genomic Advantage™
Testing volumes are rising across every therapeutic area. Without a coordinated approach, plans absorb the cost of redundant tests, out-of-network labs, and incomplete results that drive repeat ordering. Helix standardizes the pathway with Helix Genomic Advantage — one sequence, one cost, reusable results across conditions.
- Eliminate high per-test use costs: Unlimited appropriate clinical testing through Sequence Once, Query Often
- Guidelines-based care with total cost in mind: Providers can deliver top-of-license care, with immediate savings to the organization in year one PMPM-based pricing with capitation
- Maximize clinical ROI: Systemic germline testing closes hereditary risk and care gaps
- No more prior auth: Remove admin burden/cost, simplify provider workflow, eliminate patient co-pay
$5-10M in overall savings
Examining projected savings across a 200K member community hospital over 5 years
Drive outcomes and reduce cost with genomic insights
Eliminate High Per-Test Costs
Ongoing appropriate clinical testing with Sequence Once, Query Often® technology — one sample, a lifetime of value.
Projected Savings, Today
Predictable member-based pricing that aligns Helix's digital genomic capabilities to risk-entities.
Maximize Clinical ROI
Target high-value, high-ROI programs that make sense for your population and deliver measurable outcomes.
Administrative Simplicity
Remove admin burden and cost, simplify provider workflow, and eliminate patient co-pays.
Population-scale RWE that makes results more actionable
Real-world evidence (RWE) from the Helix Research Network, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.
With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.
of VUS carriers in the general population can now have their variant status resolved
of reclassified variants are confirmed Benign — giving patients clarity and peace of mind
overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results
projected VUS resolution as the dataset grows toward 2 million participants
Year one savings. Hiding in plain sight.
Aligning Helix's digital genomic capabilities to risk-entities for predictable, measurable cost reduction.
Population Risk Analysis
Helix performs a gratis analysis of your risk-entity population to determine year-one and four-year cost savings potential.
Program Design & Alignment
We align genomic testing programs to your highest-value clinical areas — oncology, cardiology, pharmacogenomics, and more.
Seamless Deployment
Integrate with existing EHR workflows and launch with predictable member-based pricing — no per-test cost surprises.
Ongoing Value with SOQO®
Sequence Once, Query Often® unlocks continuous value from a single sample — new panels, new insights, no re-collection.
Measurable Outcomes
Track clinical ROI, risk reduction, and cost savings with transparent reporting and ongoing optimization.
Receive a gratis analysis.
For organizations that take on risk — whether your employee population or ACO — Helix can perform an analysis to determine your cost savings, both year one and over four years, to understand the impact Genomic Advantage® can have on your organization today.
Year 1 Savings
Immediate cost reduction from targeted genomic programs
4-Year Projection
Compounding value as SOQO® unlocks new clinical insights
Population Shift
Move your total population from high-risk to lower-risk categories
"We’re very excited about what’s called Helix Genomic Advantage. As a benefit to anyone who has our insurance plan, they now can at no cost avail themselves of any of the genetic testing that’s on Helix’s menu. And that is a huge, huge advantage, which is why we call it Genomic Advantage."
Ready to unlock genomic value?
Connect with our team to learn how Genomic Advantage® can drive measurable outcomes and reduce costs for your organization.