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Genomics for those that set the standard

We've created the genomics platform for those who set the standard. From harnessing collective genomics intelligence to reducing the cost of genomic testing for plan members while scaling utilization—positioning your system as a recognized leader in the precision era.

Precision strategy on your terms

Every health system's genomics journey is different. Find the path that fits your goals.

Supercharge your precision strategy

We've created a genomics research network that positions health systems as leaders in leveraging collective genomic intelligence in order to advance their precision medicine strategy and enhance patient care with Helix Research Network®.

Reduce genomic testing costs

Health plan leaders know the significant value of genomics for patient care, but fee-for-service genomic testing creates unpredictable, unmanageable costs. We flipped the script with Helix Genomic Advantage™: subscription based pricing that controls cost and is designed to enable better outcomes for plan members.

Simplify clinical care pathways

Guidelines-based genomic care is fragmented across specialties, making it hard to standardize and scale across your system. With Helix Precision Pathway™, standardized, guideline-concordant care is embedded into your workflows.

Invest in savings, fund advanced care

Genomics initiatives are often siloed—screening here, testing there—creating inefficiency and making it hard to demonstrate ROI. What if test savings today could fund genomic innovation tomorrow?

Population-scale RWE that makes results more actionable

Real-world evidence (RWE) from the Helix Research Network, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.

With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.

45%

of VUS carriers in the general population can now have their variant status resolved

96%

of reclassified variants are confirmed Benign — giving patients clarity and peace of mind

9%

overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results

60%

projected VUS resolution as the dataset grows toward 2 million participants

Barrett KM, Ferber MJ, Candille S, et al. From uncertain to actionable: significant reduction in variants of uncertain significance in hereditary germline testing via multi-institutional real-world evidence. medRxiv. 2025. doi:10.1101/2025.08.12.25333547 (opens in a new tab)

Research
Care Delivery
Health Plan

Savings that compound into better care

When your health plan reduces the cost of genomic testing through Helix's subscription model, those savings can be reinvested to expand your leadership in precision care. Fund new genomics programs, expand population screening, and unlock additional research opportunities that were previously out of reach.

It's a virtuous cycle: lower costs fuel new innovations, which drive better outcomes, which justify further investment. That's compounding care.

Get to clinical value faster

Helix's unique Sequence Once, Query Often approach accelerates speed to clinical value and patient insights. Our CLIA/CAP accredited lab, proprietary Exome+® assay, and advanced analytics capabilities enable rapid results delivery - from weeks to hours (or even minutes in some cases!). This speed and depth have set the new standard for precision medicine.

TURNAROUND

Existing Patient (SOQO)®

≤ 5 days

TURNAROUND

New Patient

6–21 days

SAMPLE

Saliva, Blood, Buccal

New patient6–21 days
Existing patient≤ 5 days

Hear from our partners

Health system leaders across the country are leveraging the Helix Research Network to transform patient care, accelerate genomic discovery, and build precision medicine programs that deliver measurable impact.

See our population genomics partners.

1,500,000+ Lives in Enterprise Genomics
500K+ Exomes Sequenced
13 Year Average Longitudinal EHR History for Research Participants

Trusted by leading health systems

Medical University of South Carolina
Memorial Hermann
Cone Health
HealthPartners
The Ohio State University
UNMC Nebraska Medicine
Renown Health
Sanford Health
St. Luke's
Medical University of South Carolina
Memorial Hermann
Cone Health
HealthPartners
The Ohio State University
UNMC Nebraska Medicine
Renown Health
Sanford Health
St. Luke's

Not sure where to start?

Our team can help you map your goals to the right genomics strategy. Let's talk.