HELIX DIAGNOSTICS
Factor V Leiden and Factor II (Prothrombin) Variant Test
Test Description
Helix Factor V Leiden and Factor II (Prothrombin) Variant Test is a diagnostic test that analyzes one variant in F5 and one variant in F2 associated with factor V Leiden-related thrombophilia or prothrombin-related thrombophilia.
Note: This panel currently requires an EHR integration to order.
Genes Tested (2)
Important Panel Information
Turnaround time: 7-24 days
Preferred specimen: BD Vacutainer Whole Blood K2 EDTA Collection Tube 4mL or Oragene Dx Saliva Collection Kit
Shipping Instructions: Specimens to arrive at Helix within 96 hours of collection at ambient temperature.
This panel includes targeted variants that have an established association with factor V Leiden-related thrombophilia or prothrombin-related thrombophilia.
The targeted variants were specifically selected for their established association with these conditions. Detection of these variants may facilitate increased early-detection and prevention, as well as helping to identify at-risk family members who can pursue genetic testing and preventive measures.
All detected variants are evaluated according to American College of Medical Genetics and Genomics recommendations. Variants are classified based on known, predicted, or possible pathogenicity; however, this test only reports pathogenic and likely pathogenic variants along with interpretive comments detailing the evidence applied towards classification. Variants of uncertain significance are not reported.